Retroate ea Hydroxypinacolone
Phofo ea Hydroxypinacolone Retinoate (HPR) ke sehlahisoa se ikhethileng sa retinoic acid, motsoako o ka rekisoa tlasa lebitso la sehlahisoa "Granactive Retinoid". Hydroxypinacolone Retinoate (HPR) ke seterata sa setlolo sa ATRA, se ikhethang ke hore e sebetsana le ts'ebetso ea tlhaho ea asiti e sa sebetseng, ha e hloke ho senyeha ka mokhoa o ts'oanelang 'mele o ka fihlelang melemo ea letlalo.
| lebitso | Retroate ea Hydroxypinacolone |
| Li-synonyms | BENZAMIDE, 4-BROMO-2-FLUORO-N- (1-METHYL-4-PIPERIDINYL) -; |
| Ponahalo | Phofo e mosehla kapa kristale |
| foromo | tiileng |
| CAS | 893412-73-2 |
| Assay | 98% mets (PHLC) |
| Solubility | ha e kenelle ka metsing |
| Sebaka se belang | 508.5 ± 33.0 ° C (E boletsoe esale pele) |
| Sesebelisoa se matla | ≤20ppm |
| Storage Temp | Boloka ho -20 ° C |
| Molecular Formula | C26H38O3 |
| Boima ba 'mele | 398.58 |
| Hlakola bophelo | lilemo tse 2 |
| kopo | Motsoako oa Litlolo |
| Kereiti ya | Litlolo le sehlahisoa sa meriana |
ke eng Retroate ea Hydroxypinacolone Powder
Phofo ea Hydroxypinacolone Retinoate (HPR) ke sehlahisoa se ikhethileng sa retinoic acid, motsoako o ka rekisoa tlasa lebitso la sehlahisoa "Granactive Retinoid". Hydroxypinacolone Retinoate (HPR) ke seterata sa setlolo sa ATRA, se ikhethang ke hore e etsa ts'ebetso ea tlhaho ea asiti e sa sebetseng, ha ho hlokahale hore e senyehe ka mokhoa o ts'oanelang 'mele o ka fihlelang melemo ea letlalo. Hydroxypinacolone Retinoate (HPR) e ipakile e tsitsitse mme e baka ho halefa ha letlalo ho feta ATRA. Ntle le moo, bapisa litšobotsi tse thibelang botsofali tsa Hydroxypinacolone Retinoate (HPR) le ATRA ka ho lekola litlamorao tsa maemo a collagen le ho teneha ha letlalo mefuteng ea letlalo la organotypic. Liphetho li fana ka maikutlo a hore Hydroxypinacolone Retinoate (HPR) ke mokhoa o sebetsang ho ATRA le li-retinoid tse ling tse seng matla ho phekola letlalo le tsofetseng ntle le litlamorao tse mpe, le ho ntlafatsa ponahalo ea letlalo le tsofalang ntle le ho halefa. E ka fana ka liphetho tse tšoanang letlalong joalo ka asiti ea retinoic ha e sebelisoa. Ho latela liteko tsa moetsi oa phofo oa Hydroxypinacolone Retinoate (HPR), lihora tse 24 tsa setsi se fumanehang se nang le 0.5% HPR se bakile khalefo e tlase haholo ho feta 0.5% ea retinol. Hape, Hydroxypinacolone Retinoate (HPR) e fumaneha khaontareng ea EU, UK, Asia, New Zealand le Australia, empa e na le lengolo la ngaka feela Canada.
Retroate ea Hydroxypinacolone Powder tšebeliso
Phofo ea Hydroxypinacolone Retinoate e na le tšebetso ea ho laola metabolism ea epidermis le stratum corneum, e ka hanela botsofali, e ka fokotsa tšenyo ea sebum, ea hlapolla letlalo la letlalo, ea bapala karolo ea ho thibela botsofali ba letlalo, ho thibela makhopho, masoeu le matheba a khanyang. Ha e ntse e netefatsa ts'ebetso e matla ea retinol, e boetse e fokotsa ho teneha ha eona haholo. Ha joale e sebelisetsoa ho thibela botsofe le thibelo ea makhopho a makhopho.
Eng's Phello ea Retroate ea Hydroxypinacolone Powder
1) Ha ho kotsi ea liphetoho tse mpe, tšusumetso e tlase
2) Mosebetsi o phahameng
3) botsitso bo betere
4) Ka lebaka la phello e tobileng ea super VA, litlamorao tsohle li potlakile ho feta phello ea setso sa retinol. Phello ea anti-wrinkle e sebetsa pele ho matsatsi a 14.
Moo u ka rekang phofo ea Hydroxypinacolone Retinoate Inthaneteng?
Kaha baetsi le mohopolo li fapana, tse nang le thekiso ea phofo ea Hydroxypinacolone Retinoate (HPR) le eona e na le mohloli o fapaneng. E ka laeloa habonolo phofo ea Hydroxypinacolone Retinoate (HPR) inthaneteng ho tsoa ho bahlahisi le barekisi ba bangata.
Bakeng sa merero e meng ea litsebi, ho sebelisa Powder ea Hydroxypinacolone Retinoate (HPR) ka bohloeki bo phahameng le boleng bo ikhethang ho bohlokoa haholo. Kahoo, ho odara lihlahisoa tsa boleng bo holimo tse tsoang ho baetsi ba tšepahalang ho a thusa.
CMOAPI ke e 'ngoe ea baetsi ba phofo ea Hydroxypinacolone Retinoate (HPR) e nang le moetlo oa nako e telele indastering mme e netefatsa phofo ea boleng bo holimo le e pakiloeng hantle ea Hydroxypinacolone Retinoate (HPR).
Tlanya Mona ho Place Yrona Olekala
Beha otara ea hau mona ho nka lihlahisoa tsa boleng bo holimo tsa 98OAPI tsa boleng bo phahameng ba XNUMX% tsa litlolo tse hloekileng Hydroxypinacolone Retinoate (HPR). Phofo ea rona ea Hydroxypinacolone Retinoate (HPR) ke GMP le DMF, e leng tiiso ea mantlha ea hore re isa lihlahisoa tsa boleng bo holimo ho bareki ba rona ka bomong.
Reference
1. Ruth, N., le T. Mammone. "Litlamorao tsa ho thibela botsofali tsa 1310 tsa retinoid hydroxypinacolone retinoate mefuteng ea letlalo." Leqephe la Phuputso ea Dermatology 138.5 (2018): S223.
2.Giornale italiano di dermatologia e venereologia, 2015 Apr; 150 (2): 143-7., Phekolo ea makhopho a bonolo ho isa ho a itekanetseng ka motsoako o tsitsitseng oa hydroxypinacolone retinoate, retinol glycospheres le papain glycospheres.
3.Giornale Italiano di Dermatologia e Venereologia, 2016/03, Ts'ebetso le polokeho ea kalafo ea likhoeli tse 12 ka motsoako oa hydroxypinacolone retinoate le retinol glycospheres joalo ka kalafo ea tlhokomelo ho bakuli ba makhopho kamora 'isotretinoin ea molomo.
